Skin-nontumor - Acute eczematous dermatitis

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Other dermatoses

Acute eczematous dermatitis

Reviewer: Mowafak Hamodat MB.CH.B, MSc., FRCPC, Eastern Health, St. Johns (Canada) (see Reviewers page)
Revised: 19 July 2011, last major update July 2011
Copyright: (c) 2002-2011, PathologyOutlines.com, Inc.

Definition
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● Allergic contact dermatitis: click here
● Atopic dermatitis: pruritic disease of unknown origin; usually begins in infants; eczematous lesions, lichenification (thickening with increase in skin markings), dry skin; may be familial (hay fever, asthma, and eczema); occurs on flexural surfaces (eMedicine)
● Drug-related: usually systemic (penicillin); eosinophils present in deep dermis
● Eczema: red, papulovesicular, oozing and crusted lesions (spongiotic dermatitis) which evolve to raised, scaling plaques (epidermal hyperplasia and excessive scale)
● Irritant contact dermatitis: click here
● Photo-dermatitis: due to UV light exposure
● Primary irritant dermatitis: due to repeated rubbing

Treatment
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● Potential allergens should be identified and avoided
● Topical steroid ointments and tars are the mainstays of therapy
● Clobetasol combined with zinc sulfate cream may be more effective than clobetasol alone (J Eur Acad Dermatol Venereol 2008;22:531)

Gross images
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Atopic dermatitis

Micro description
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● Spongiosis, perivascular lymphocytic infiltrate
● Superficial dermal edema

Differential diagnosis
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● Drug reaction: prominent eosinophilic infiltrate

End of Skin-nontumor > Other dermatoses > Acute eczematous dermatitis

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