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Salivary glands

Authors: Karina Aivazian, M.B.B.S., Derek Allison, M.D., F. Zahra Aly, M.D., Ph.D., Saeed Asiry, M.D., Rebecca Tian Mei Au, M.B.B.S., Sapna Balgobind, M.B.B.Ch., Nazim Benzerdjeb, M.D., Ph.D., Tamar C. Brandler, M.D., M.S., Manish Mahadeorao Bundele, M.B.B.S., M.D. , Rebecca Chernock, M.D., Chun Chau Lawrence Cheung, M.D., Jonathan Clark, M.B.B.S., Kim A. Ely, M.D., Timothy Fielder, M.B.B.S., B.Med.Sci., Umamaheshwari Golconda, M.D., Ruta Gupta, M.D., Jose Manuel Gutierrez Amezcua, M.D., Adriana Handra-Luca, M.D., Ph.D., Jen-Fan Hang, M.D., Theoni Haralabopoulos, M.D., Min Li Huang, M.B.B.S., Jalal B. Jalaly, M.B.B.S., M.S., Treeva Jassim, M.D., Arash H. Lahoutiharahdashti, M.D., Kelly Magliocca, D.D.S., M.P.H., Zahra Maleki, M.D., Michael Mikula, M.D., Diana Murro Lin, M.D., Alice Ormandy, M.B.B.S., M.P.H., Nat Pernick, M.D., Natasha Prosser, B.Sc., M.B.B.S., Rema A. Rao, M.D., Lisa Rooper, M.D., Abeer Salama, M.D., Sadia Sayeed, M.D., Molly Housley Smith, D.M.D., Lulu Sun, M.D., Ph.D., Aditya Talwar, M.D., Sally Tanakchi, M.D., Shuanzeng (Sam) Wei, M.D., Ph.D., Bin Xu, M.D., Ph.D., Xiaofeng Zhao, M.D., Ph.D.

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Editorial Board oversight: Marc Pusztaszeri, M.D. (last reviewed December 2022), Lisa Rooper, M.D. (last reviewed December 2021)
Table of contents
General:anatomy & histology books grossing, frozen section & features to report staging-major salivary glands WHO classification (pending)
Cytology
Fine needle aspiration:FNA-general
Milan system:Milan reporting system for salivary gland cytopathology atypia of undetermined significance (AUS) malignant neoplasm-benign neoplasm-salivary gland neoplasm of uncertain malignant potential (SUMP) nondiagnostic nonneoplastic suspicious for malignancy
Developmental disorders:heterotopia oncocytosis (pending)
Inflammatory:HIV salivary gland disease (HIV-SGD) (pending) IgG4 related sialoadenitis lymphoepithelial sialadenitis necrotizing sialometaplasia sialadenitis-infectious chronic sialadenitis / sialolithiasis Sjögren syndrome
Nonneoplastic tumors / tumor-like conditions:adenomatoid hyperplasia and sialadenosis intercalated duct hyperplasia lipomatosis lymphoepithelial cyst mucocele / ranula (pending) nodular oncocytic hyperplasia salivary duct cyst
Primary salivary gland neoplasms:primary salivary gland neoplasms-general genetic alterations in salivary gland tumors (pending)
Benign:basal cell adenoma canalicular adenoma cystadenoma ductal papilloma keratocystoma lymphadenoma myoepithelioma oncocytoma pleomorphic adenoma sclerosing polycystic adenoma sialadenoma papilliferum striated duct adenoma (pending) Warthin tumor
Malignant:acinic cell carcinoma adenocarcinoma, NOS adenoid cystic carcinoma basal cell adenocarcinoma carcinoma ex pleomorphic adenoma carcinosarcoma clear cell carcinoma epithelial myoepithelial carcinoma intraductal carcinoma lymphoepithelial carcinoma microsecretory adenocarcinoma mucinous adenocarcinoma (pending) mucoepidermoid carcinoma myoepithelial carcinoma neuroendocrine carcinoma polymorphous adenocarcinoma salivary duct carcinoma sclerosing microcystic adenocarcinoma sebaceous adenocarcinoma (pending) secretory carcinoma sialoblastoma squamous cell carcinoma
Other tumors:extranodal marginal zone MALT lymphoma lipoma / sialolipoma metastases nodular fasciitis
Salivary gland stains: androgen receptor beta catenin calponin CK5/6 and CK5 CK7 DOG1 GATA3 GFAP HER2 HMGA2 IgG4 KIT LEF1 mammaglobin mucicarmine MYB NR4A3 (pending) p40 p63 pan-TRK PLAG1 S100 SMA SOX10

Superpages: entire chapterimagesvirtual slides
Index (Alphabetical table of contents)
A-E:acinic cell carcinoma adenocarcinoma, NOS adenoid cystic carcinoma adenomatoid hyperplasia and sialadenosis anatomy & histology atypia of undetermined significance (AUS) basal cell adenocarcinoma basal cell adenoma canalicular adenoma carcinoma ex pleomorphic adenoma carcinosarcoma chronic sialadenitis / sialolithiasis clear cell carcinoma cystadenoma ductal papilloma epithelial myoepithelial carcinoma extranodal marginal zone MALT lymphoma
F-N:FNA-general genetic alterations in salivary gland tumors (pending) grossing, frozen section & features to report heterotopia HIV salivary gland disease (HIV-SGD) (pending) IgG4 related sialoadenitis intercalated duct hyperplasia intraductal carcinoma keratocystoma lipoma / sialolipoma lipomatosis lymphadenoma lymphoepithelial carcinoma lymphoepithelial cyst lymphoepithelial sialadenitis malignant metastases microsecretory adenocarcinoma Milan reporting system for salivary gland cytopathology mucinous adenocarcinoma (pending) mucocele / ranula (pending) mucoepidermoid carcinoma myoepithelial carcinoma myoepithelioma necrotizing sialometaplasia neoplasm-benign neoplasm-salivary gland neoplasm of uncertain malignant potential (SUMP) neuroendocrine carcinoma nodular fasciitis nodular oncocytic hyperplasia nondiagnostic nonneoplastic
O-Z:oncocytoma oncocytosis (pending) pleomorphic adenoma polymorphous adenocarcinoma primary salivary gland neoplasms-general salivary duct carcinoma salivary duct cyst sclerosing microcystic adenocarcinoma sclerosing polycystic adenoma sebaceous adenocarcinoma (pending) secretory carcinoma sialadenitis-infectious sialadenoma papilliferum sialoblastoma Sjögren syndrome squamous cell carcinoma staging-major salivary glands striated duct adenoma (pending) suspicious for malignancy Warthin tumor WHO classification (pending)
Salivary glands books

Bishop: 2021

Cardesa: 2016

Carlson: 2015

Faquin: 2023

Franchi: 2020

García : 2019

Gnepp: 2020

IARC: 2024

Jiang: 2023

Mody: 2022

Neville: 2023

Stelow: 2020

Thompson: 2022

VandenBussche: 2017

Wenig: 2017



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