Salivary glands
Non-neoplastic tumors and tumor-like conditions
Epidermoid cyst

Author: Sally Tanakchi, M.B.Ch.B. (see Authors page)
Editor: F. Zahra Aly, M.D., Ph.D.

Revised: 30 October 2015, last major update October 2015

Copyright: (c) 2002-2015,, Inc.

PubMed Search: Epidermoid cyst [title] salivary
Cite this page: Epidermoid cyst. website. Accessed January 16th, 2018.
Definition / general
  • Very rare in salivary glands with few reports of involvement of major salivary glands
  • Histogenesis thought to be ectodermal, and derived from remnants of branchial pouch epithelium
  • Since easily mistaken for salivary gland abscess, neoplasm or other cysts, excision required for diagnosis and treatment
Case reports
Clinical images
Missing Image

No surface discharge

Missing Image

Mobility in teeth

Missing Image

Salivary gland swelling

Gross images
Missing Image

Globular mass

Missing Image

Parotidectomy specimen

Microscopic (histologic) description
  • Unilocular cyst with squamous lining containing a granular layer, usually filled with cheesy material or keratin
Microscopic (histologic) images
Missing Image Missing Image

Stratified squamous epithelium

Missing Image

Mature squamous cells

Missing Image

Parotid acini