Placental findings in specific newborn/fetal or maternal conditions
Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 17 November 2011, last major update November 2011
Copyright: (c) 2003-2011, PathologyOutlines.com, Inc.
● A single umbilical artery is more common in trisomic pregnancies
● Early spontaneous abortions may show no fetal parts and an absent umbilical cord (Hum Pathol 1995;26:201)
● Trisomy 21: elevated serum hcG and inhibin, reduced serum estradiol and AFP
● Trisomy 18: low serum hcG, low AFP, low inhibin and low estradiol
● Large hypovascular / avascular villi with irregular borders accompanied by normal-appearing villi
● Villous hydrops is also seen, though less than in other abnormal karyotypes
End of Placenta > Placental findings in specific newborn/fetal or maternal conditions > Fetal trisomies
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.
All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at [email protected] with any questions (click here for other contact information).