Table of Contents
Definition / general | Etiology | Gross description | Microscopic (histologic) description | Microscopic (histologic) imagesCite this page: Ziadie MS. Hydrops fetalis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/placentahydrops.html. Accessed November 29th, 2024.
Definition / general
- Massive generalized fetal edema due to a variety of processes
Etiology
- Immune related: hemolytic disease of the newborn, previously the most common cause of hydrops fetalis
- Nonimmune related: chromosomal abnormalities, infection, congenital cardiac / other anomalies, anemia, metabolic disorders and fetal tumors
Gross description
- Edematous placenta
Microscopic (histologic) description
- Villous stromal edema with erythroblastosis (increased fetal nucleated red cells) and possibly intravillous hematopoiesis
- No trophoblastic hyperplasia or cisterns (Hum Pathol 1985;16:785)