Placental gross/microscopic abnormalities, non-neoplastic
Reviewers: Mandolin Ziadie, M.D. (see Reviewers page)
Revised: 10 October 2011, last major update October 2011
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● Fluid filled spaces in the placental membranes, beneath the chorionic plate or within cell islands or septa
● May be associated with chronic uterine hypoxia (Pediatr Dev Pathol 2011;14:1)
● Thought to be due to ischemia and degeneration
● When visible grossly, cysts are usually small (<3 cm) and bulge into the amnionic cavity from the fetal surface
● Differential diagnosis of grossly visible cysts includes partial moles
● Spaces filled with eosinophilic proteinaceous material and lined by extravillous trophoblastic cells
End of Placenta > Placental gross/microscopic abnormalities, non-neoplastic > Chorionic cysts
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