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Various drawings of ovary

Case reports

Gross images

Corpus luteum


With follicular cysts

Micro images


Primordial follicles and primary follicles

Secondary follicle

Tertiary follicle

Graafian follicle

Mature follicles

Granulosa cells of proliferating
follicle exhibit marked
mitotic activity

Ruptured follicle

Atretic follicle

Normal histology:

Surface epithelium

Surface epithelial stromal proliferation

Vacuolar change within surface epithelial inclusion glands

Surface epithelial inclusion glands

Ovarian stroma

Luteinized stromal cells


Hilus cells


Rete ovarii

Walthard nest

Corpus luteum:


Of menstruation

Involuting at menstruation

Corpus luteum of pregnancy


Mesothelial hyperplasia (left to right): #1-present between outer surface of an ovarian serous borderline tumor (left) and vascular adhesion (right); #2-mesothelial cells have abundant pale eosinophilic cytoplasm, small focus of calcification is evident; #3-numerous small tubular structures and cords of mesothelial cells are growing in a parallel array

Adrenocortical rest in mesosalpinx

Artifact: granulosa cells in blood vessel lumina

Infarcted appendix epiploica attached to ovarian surface, with focal calcification

Pregnancy-related changes:

Granulosa cell proliferation: an atretic follicle is filled with a proliferation of granulosa cells growing in a pattern resembling a microfollicular granulosa cell tumor (left); the granulosa cell layer of a cystic atretic follicle is replaced by solid tubules resembling a Sertoli cell tumor-the tubules are surrounded by a layer of theca lutein cells (right)

Ectopic decidua: one cell is vacuolated, somewhat resembling a signet- ring cell (left); large nodules were present on the ovarian and peritoneal surfaces, the cells have abundant eosinophilic cytoplasm and central, pale, round nuclei (right)


Post-menopausal: atrophic ovary (left); cortical granuloma (right)

Hilus cell hyperplasia: large nodular masses of hilus cells are present, one surrounding the rete ovarii (left); post-menopausal woman whose hilus cells have bizarre shapes and abundant eosinophilic cytoplasm, some nuclei are enlarged and hyperchromatic (right)

Nodular hilar cell proliferation

Positive stains

Negative stains


Corpus luteum

Corpus albicans

End of Ovary - nontumor > Normal histology


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