Ovary - nontumor
Nonneoplastic cysts / other

Author: Mohiedean Ghofrani, M.D. (see Authors page)

Revised: 19 September 2017, last major update August 2011

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Ovarian endosalpingiosis

Cite this page: Ghofrani, M. Endosalpingiosis. PathologyOutlines.com website. http://pathologyoutlines.com/topic/ovarynontumorendosalpingiosis.html. Accessed December 15th, 2017.
Definition / general
  • Presence of benign glands, lined by tubal type epithelium
  • Typically in women of reproductive age
  • Most commonly pelvic peritoneum covering uterus, fallopian tubes, ovaries and cul de sac
  • Other sites also reported
  • Origin from secondary mullerian system (pelvic and lower abdominal mesothelium) is favored
  • Association with chronic salpingitis suggests implantation of sloughed tubal epithelium as another possibility
  • Also, association with ovarian serous tumors, usually borderline, suggests maturation of tumor implants
Clinical features
  • Almost always an incidental finding
Case reports
Gross description
  • Usually grossly inapparent but may present as multiple white to yellow microcysts (1 - 2 mm)
  • Rarely seen as larger cysts
Microscopic (histologic) description
  • Benign glands and tubules lined by tubal type cells
  • May be surrounded by loose stroma with chronic inflammatory infiltrate
  • Calcifications or psammoma bodies are common (Mod Pathol 2003;16:219)
  • Smooth contours
  • Variable papillae beneath the peritoneal surface
Microscopic (histologic) images

Images hosted on PathOut server:

Glands lined by ciliated epithelium lie in fibrous stroma

Ciliated, secretory and intercalated cells line cystic space

Images hosted on other servers:

Lymph node

Omentum: CD34 and calretinin

Differential diagnosis