Oral cavity & oropharynx
Inflammatory / immune mediated (noninfectious)
Granulomatous inflammation
Author: Charu Thakral, M.D.
Last author update: 1 February 2013
Last staff update: 27 October 2023
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PubMed Search: Granulomatous inflammation oral cavity
Table of Contents
Definition / general | Case reports | Treatment | Clinical images | Microscopic (histologic) imagesCite this page: Thakral C. Granulomatous inflammation. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/oralcavitygranulomatousinflamm.html. Accessed April 19th, 2024.
Definition / general
- Associated with chronic recurrent tonsillitis
- Usually benign course, no specific organism recovered
- Must rule out infectious causes (tuberculosis, tertiary syphilis, salmonella, mycotic granulomas), systemic causes (sarcoidosis, Crohn's, Granulomatosis with polyangiitis (Wegener's), eosinophilic granuloma), foreign body reaction, cholesterol granuloma
- Idiopathic orofacial granulomatosis: condition restricted to oral and maxillofacial region without any identifiable systemic granulomatous disease
Case reports
- 9 year old girl with idiopathic orofacial granulomatosis (J Oral Maxillofac Pathol 2012;16:432)
- 11 year old boy with idiopathic orofacial granulomatosis (J Indian Soc Periodontol 2012;16:469)
Treatment
- Individualized and often needs to change for each patient; includes corticosteroids or other drugs, gingivectomy
Clinical images
Images hosted on other servers:
9 year old girl:
Preoperative
1 year follow up
11 year old boy:
Preoperative
Postoperative
Microscopic (histologic) images
Images hosted on other servers:
Multiple granulomas
Lip and gingival biopsies
Granulomatous lesion and infiltrates
