Cytopathology Competency Assessment
Cysts & Inflammation

Author: Gordon H. Yu, M.D. (see Authors page)

Revised: 31 May 2016, last major update September 2012

Copyright: (c) 2003-2016,, Inc.

Cite this page: Cytology/Competency Assessment - Cysts & Inflammation . website. Accessed January 19th, 2018.
Medical Knowledge, Practice Based Learning and Systems Based Practice
  1. Mediastinal Cysts
    1. Recognize the differential diagnosis of cystic lesions in the mediastinum (benign, developmental cysts vs. cystic neoplasms)
    2. Recognize the most common location of these lesions, their origin and expected clinical behavior
    3. Recognize possible contaminating cell types which may be encountered in mediastinal FNAs (i.e. mesothelial cells, respiratory epithelium)
    4. Recognize common cytologic findings observed in FNA specimens of cystic mediastinal lesions
      1. Developmental cysts (gastroenteric, bronchogenic, esophageal, neurogenic cysts)
      2. Pericardial (mesothelial) cysts
      3. Lymphangioma
      4. Thymic cysts
      5. Other cysts
        • Identify mediastinal neoplasms which may present as a cystic mass (either predominantly cystic or with a prominent cystic component)
  2. Inflammatory Lesions
    1. Acute mediastinitis
      1. Recognize causes of acute mediastinitis, the most frequent compartment affected and typical FNA findings
    2. Granulomatous mediastinitis
      1. Identify common organisms which may cause granulomatous mediastinitis
      2. Recognize the differential diagnosis of granulomas in FNA of a mediastinal mass, including neoplasms and inflammatory conditions
    3. Chronic sclerosing mediastinitis
      1. Identify the most frequent compartment affected
      2. Identify typical FNA findings and frequently associated conditions elsewhere in the body