Lymph nodes - not lymphoma
Normal lymphocyte development
Reviewer: William D. DePond, M.D. (see Reviewers page)
Revised: 3 July 2013, last major update June 2006
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
- Normal lymphoid cells undergo rearrangements within their antigen receptor genes, causing specificity for the immunoglobulin or T cell receptor that they produce
- Monoclonal proliferations are presumed to be neoplastic; polyclonal populations are not
- Apoptosis helps eliminate B cells producing antibodies with low avidity
- Lymphoid stem cell: TdT+, CD34+, HLA-DR+, then develops along B or T cell pathway
End of Lymph nodes - not lymphoma > Normal > Normal lymphocyte development
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.
All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com
with any questions (click here for other