Lung tumor
Other carcinoma
Epithelial-myoepithelial carcinoma

Author: Deepali Jain, M.D. (see Authors page)

Revised: 22 December 2016, last major update September 2012

Copyright: (c) 2003-2016,, Inc.

PubMed Search: Epithelial-myoepithelial carcinoma lung
Cite this page: Epithelial-myoepithelial carcinoma. website. Accessed June 27th, 2017.
Definition / general
  • Low grade malignancy that arises from submucosal bronchial glands, mimics similar salivary gland tumor
  • Very rare, < 20 cases reported through 2009
  • Ages 40-69 years
  • Long interval to recurrence or metastasis
Case reports
Gross description
  • Intraluminal polypoid mass in bronchus; may invade pulmonary parenchyma
Gross images

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Incidental endobronchial mass

Microscopic (histologic) description
  • Well circumscribed mass, pushing margin
  • Biphasic proliferation of epithelial and myoepithelial cells with formation of bilayered ductlike structures
  • Tumor consists of ductlike structures with inner epithelial cells and outer clear myoepithelial cells
  • No myxoid / chondroid stroma, no perineural invasion (Hum Pathol 2009;40:366)
Microscopic (histologic) images

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Case of the Week #357:

Lung biopsy

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Various images

Incidental endobronchial mass:








Positive stains
Negative stains
Differential diagnosis