Lung tumor
Other malignancies
Angiosarcoma

Author: Deepali Jain, M.D. (see Authors page)

Revised: 3 January 2017, last major update September 2012

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed Search: pulmonary angiosarcoma
Cite this page: Angiosarcoma. PathologyOutlines.com website. http://pathologyoutlines.com/topic/lungtumorangiosarcoma.html. Accessed March 27th, 2017.
Definition / General
  • Presents as mass or diffuse pulmonary infiltrates, usually in adult men (Ann Diagn Pathol 2010;14:296)
  • Almost all cases in lung represent metastatic disease
Case Reports
Gross Description
  • Diffusely hemorrhagic lungs with multiple dark red nodules
  • Involves interlobar septa and bronchovascular bundles
  • Grows along lymphatics or venous routes
Gross Images

Images hosted on other servers:

Metastatic tumor at autopsy has multiple cystic nodules

Micro Images

Images hosted on other servers:

Primary angiosarcoma of lung shows (left to right): interanastomosing vascular spaces, tumor cells with atypia and hobnailing that dissect vascular spaces, solid sheets of epithelioid cells, primitive vessel formation


Primary epithelioid (left) and metastatic (right) disease

Differential Diagnosis
  • Metastatic angiosarcoma