Lung tumor
Other carcinoma
Adenoid cystic carcinoma

Author: Deepali Jain, M.D. (see Authors page)

Revised: 21 December 2016, last major update September 2012

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed Search: adenoid cystic carcinoma lung
Cite this page: Adenoid cystic carcinoma. PathologyOutlines.com website. http://pathologyoutlines.com/topic/lungtumorACC.html. Accessed January 23rd, 2017.
Definition / General
  • #2 most common salivary gland tumor of lung, may arise from submucus bronchial glands
  • Usually in large bronchi, may involve the trachea
  • M:F 2:1
  • Prolonged course, but overall prognosis is poor
  • Frequent metastases to regional lymph nodes and lung parenchyma
Treatment
  • Radiation therapy (palliative)
Gross Description
  • Large, centrally located, polypoid, intrabronchial mass, or may grow subepithelially along bronchi causing thickened bronchial wall
Gross Images

Images hosted on other servers:

75 year old woman with 1 cm lung lesion

Micro Description
  • Cylindromatous, tubular, and solid patterns of microcystic spaces containing mucin, surrounded by small tumor cells
  • Defining features are pseudocysts (rounded extracellular space containing basal lamina), intercellular spaces, basal lamina and true glandular lumens (Hum Pathol 1982;13:916)
Micro Images

Images hosted on other servers:

14 year old girl with 11 cm lung mass

75 year old woman with 1 cm lung lesion: H&E, TTF1


Various images

Differential Diagnosis