Cite this page: Sequestrations (intralobar and extrapulmonary lobar). PathologyOutlines.com website. http://pathologyoutlines.com/topic/lungnontumorsequestrations.html. Accessed March 30th, 2017.
Definition / General
- Lobes or segments of lung without a normal connection to the airway system (eMedicine)
- Arterial blood supply is from aortic branches, NOT pulmonary arteries
- Extrapulmonary sequestrations: external to lung, covered with separate pleural lining, may be anywhere in thorax or mediastinum; usually infants; abnormal masses, 90% on left side, 20% have other congenital anomalies; associated with polyhydramnios and edema; Venous drainage is into azygous system (Ultrasound Obstet Gynecol 2006;27:214)
- Intralobar sequestrations: within the lung, usually lower lobe, segment is supplied by a large artery from aorta, not invested with its own pleura; associated with infections: bronchiectasis, chronic inflammation, and fibrosis; venous drainage is into pulmonary vein
- 25 year old man with mediastinal mass (Ann Thorac Surg 1997;63:1169)