Lung - nontumor
Other nonneoplastic disease
Pulmonary edema

Author: Elliot Weisenberg, M.D. (see Authors page)

Revised: 22 March 2017, last major update December 2011

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed search: pulmonary edema [title] lung

Table of Contents
Clinical features
Cite this page: Pulmonary edema. PathologyOutlines.com website. http://pathologyoutlines.com/topic/lungnontumorpulmonaryedema.html. Accessed December 15th, 2017.
Clinical features
  • Due to hemodynamic disturbances (cardiogenic) or local microvascular injury

Hemodynamic disturbances:
  • Due to increased hydrostatic pressure from congestive heart failure
  • Lungs are wet and heavy, fluid initially at base of lower lobes because hydrostatic pressure is greater here
  • Congestion, fluid and hemosiderin laden macrophages (heart failure cells) are present
  • Later fibrosis and thickening of alveolar walls (brown induration of lung)

Local microvascular injury:
  • Injury causes leakage of fluids and proteins into interstitial space, eventually into alveoli
  • When diffuse, contributes to acute respiratory distress syndrome