Liver and intrahepatic bile ducts - nontumor
Viral hepatitis
General

Author: Komal Arora, M.D. (see Authors page)

Revised: 3 November 2017, last major update May 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Viral hepatitis liver general[TI]

Table of Contents
Definition / general
Cite this page: Arora, K. Viral hepatitis - general. PathologyOutlines.com website. http://pathologyoutlines.com/topic/liverviralhepgeneral.html. Accessed December 14th, 2017.
Definition / general
  • Infections differ if host is immunocompromised
  • Hepatotrophic viruses are A, B, C, delta agent, E, G
  • May be self limiting (hepatitis A), cause chronic liver disease and cirrhosis (hepatitis B and C), cause massive necrosis and acute liver failure (rare with hepatitis C)

Viruses that infect liver and other organs:
  • Adenovirus
  • Crimean / Congo hemorrhagic fever (Russia, Africa, Pakistan, Iraq, Dubai)
  • Ebola (Africa)
  • Enteroviruses
  • Junin hemorrhagic fever (Argentina)
  • Lassa fever (Nigeria)
  • Machupo hemorrhagic fever (Bolivia)
  • Marburg virus (Uganda green monkeys)
  • Measles (rubeola)
  • Rift valley fever (Africa)
  • Rubella
  • Yellow fever

Carrier state:
  • Virus present but either no clinically apparent disease or chronic hepatitis
  • Best characterized for hepatitis B
  • Present in 90% infected early in life or at childbirth versus 1 - 10% of adult infections with hepatitis B
  • Associated with impaired immunity