Liver and intrahepatic bile ducts - nontumor
Vascular disorders
General

Author: Komal Arora, M.D. (see Authors page)

Revised: 9 November 2017, last major update May 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Vascular disorders[TIAB] liver[TI]

Table of Contents
Definition / general
Cite this page: Arora, K. Vascular disorders - general. PathologyOutlines.com website. http://pathologyoutlines.com/topic/livervasculargeneral.html. Accessed December 14th, 2017.
Definition / general
  • Due to obstruction to inflow (hepatic artery or portal vein) or outflow (central veins, major hepatic veins, inferior vena cava, congestive heart failure) or severe hypotension
  • Normal liver is resistant to ischemia due to dual inflow and possibly also collaterals
  • Obstruction of outflow causes central passive congestion, leading to hepatocellular atrophy and centrilobular fibrosis that may obliterate central vein lumina
  • Causes of outflow obstruction: radiotherapy, alkylating agents, comfrey tea