Liver and intrahepatic bile ducts - tumor
Benign tumors / conditions
Lymphangioma

Author: Deepali Jain, M.D. (see Authors page)

Revised: 17 November 2017, last major update February 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Lymphangioma[TI] liver

Cite this page: Jain, D. Lymphangioma. PathologyOutlines.com website. http://pathologyoutlines.com/topic/livertumorlymphangioma.html. Accessed November 19th, 2017.
Definition / general
  • Very rare; < 25 cases reported (Hepatol Int 2010;4:784, Surg Today 2010;40:883)
  • Male predominance, age ranges from newborn to 66 years; 1 - 25 cm, solitary
  • Liver involvement is part of multicentric process affecting other organs, particularly spleen
  • May be congenital or benign slow growing tumor derived from proliferating lymph ducts, inflammatory and fibrotic processes or genetic predisposition
  • May represent mesenchymal hamartoma
Gross description
  • Well defined solid and cystic tumor with or without spotty calcification
Gross images

Images hosted on other servers:

Cystic and smooth mass includes gallbladder

Microscopic (histologic) description
  • Cystic tumor with colloid-like content and attenuated endothelial-like cells, no atypia
Microscopic (histologic) images

Images hosted on other servers:

Multiple cystic spaces lined by endothelium

Positive stains
Differential diagnosis
  • Hemangioma: negative for lymphatic endothelial markers