Liver and intrahepatic bile ducts - tumor
Other malignancies
Leiomyosarcoma

Author: Deepali Jain, M.D. (see Authors page)

Revised: 4 December 2017, last major update February 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Leiomyosarcoma[TI] liver[TI]

Cite this page: Jain, D. Leiomyosarcoma. PathologyOutlines.com website. http://pathologyoutlines.com/topic/livertumorLMS.html. Accessed December 15th, 2017.
Definition / general
  • Rare (< 30 cases reported) aggressive malignant smooth muscle neoplasm, usually postmenopausal women, characterized by neoplastic spindle cells (IARC: 8890 / 3 Leiomyosarcoma, NOS [Accessed 4 December 2017])
  • Tumors either primary in liver or arise in ligamentum teres or inferior vena cava
  • Associated with HIV, posttransplantation in children and Budd-Chiari syndrome
  • Usually causes death within 2 years
Case reports
Clinical images

Images hosted on other servers:

67 year old man

Microscopic (histologic) images

Images hosted on other servers:

Liver metastases of
rectal carcinoma (left)
and primary hepatic
leiomyosarcoma (right)

67 year old man with 1.3 kg mass

Differential diagnosis