Liver and intrahepatic bile ducts - tumor
Kaposiís sarcoma (KS)
Reviewers: Deepali Jain, M.D. (see Reviewers page)
Revised: 9 January 2013, last major update February 2012
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See also Soft Tissue Tumors chapter
● Malignant vascular neoplasm with blunt endothelial cells, erythrocyte extravasation, hemosiderin deposition, usually in HIV+ patients; incidental finding at autopsy in 15% with AIDS (WHO)
● Present in liver in 12-25% of fatal cases of KS elsewhere in body
● Hemorrhagic multifocal spongy nodules, 5-7 cm
Multiple dark brown lesions in large portal areas
● Spindle cells with hyaline globules and vasoformative channels with extravasated red blood cells
● Lesions centered on portal tracts
Spindle cells and slit-like vascular spaces
● CD31, CD34
● Bacillary peliosis hepatis
End of Liver and intrahepatic bile ducts - tumor > Other malignancies > Kaposiís sarcoma (KS)
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