Liver and intrahepatic bile ducts - nontumor
Metabolic diseases
Heme oxygenase-1 deficiency

Author: Komal Arora, M.D. (see Authors page)

Revised: 27 October 2017, last major update April 2012

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PubMed Search: Heme oxygenase-1 deficiency

Cite this page: Arora, K. Heme oxygenase-1 deficiency. PathologyOutlines.com website. http://pathologyoutlines.com/topic/liverHO1deficiency.html. Accessed November 20th, 2017.
Definition / general
  • Enzyme degrades heme into biliverdin, carbon monoxide and free iron; also is antioxidant and has role in iron balance (J Cell Mol Med 2009;13:3091)
Case reports
Microscopic (histologic) description
  • Amyloid present in liver and adrenal glands, mesangioproliferative glomerular changes in kidney, fatty streaks and fibrous plaques in aorta