Kidney tumor - cysts, children, adult benign
Childhood neoplasms
Renal cell carcinoma in children

Author: Mandolin Ziadie, M.D. (see Authors page)

Revised: 17 January 2017, last major update January 2012

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed Search: Renal cell carcinoma [title] children

Cite this page: Renal cell carcinoma in children. PathologyOutlines.com website. http://pathologyoutlines.com/topic/kidneytumorrccchildren.html. Accessed January 18th, 2017.
Epidemiology
Case Reports
Treatment
Micro Description
  • Pediatric papillary RCC shares histologic, immunohistochemical and molecular features with adult papillary RCC
  • Xp11.2 translocation RCC shows cells with abundant clear or granular eosinophilic cytoplasm arranged in papilla or nests
  • t(6;11) RCC is composed of epithelioid cells with abundant cytoplasm, well - defined borders and small round nuclei arranged in nests / tubules
Positive Stains
  • Xp11.2 translocation RCC: TFE3 (nuclear)
  • t(6;11) RCC: TFEB (nuclear)
Negative Stains
Additional References