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Extrahepatic bile ducts



Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 16 February 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.


● Rare; multiple and recurrent papillary adenomas in biliary tract, usually involving extrahepatic bile ducts
● Also called adenomatosis
● Usually ages 50-60 years, no gender preference

Case reports

● 63 year old man with intrahepatic and extrahepatic biliary papillomatosis (Arch Pathol Lab Med 1993;117:944)
● 65 year old man who received photodynamic therapy for recurrent biliary papillomatosis (World J Gastroenterol 2008;14:4234)
● 75 year old man (Ann Pathol 2004;24:364)
● 82 year old man with biliary papillomatosis of the common hepatic duct (Ann Ital Chir 2011;82:405)


● Complete excision, but local recurrence is common

Gross description

● Dilated bile ducts with thick, fibrotic walls
● Entire mucosal surface may be replaced by papillary adenomas
● Intraluminal mucin common
● Adenomas are tan, soft, friable polyps without gross invasion

Micro description

● Columnar or cuboidal cells with basal nuclei overlying fibrovascular core

Micro images

Various images

End of Extrahepatic bile ducts > Tumors > Papillomatosis

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