Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 13 February 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
● Usually secondary to inflammatory disorders (chronic cholecystitis [5-20%] or cholelithiasis, adenomyomatous hyperplasia, primary sclerosing cholangitis, ulcerative colitis), cholesterolosis (up to 100%) or anomalous arrangement of pancreaticobiliary duct (40-90%)
● Diffuse or focal
● 12 year old girl with biliary colic
(J Pediatr Surg 2001;36:1584)
● Primary diffuse papillary hyperplasia of gallbladder (Pathology 2006;38:591)
● Single layer of columnar epithelium in papillary mucosal folds, may be villiform
● Basal nuclei, no atypia
End of Gallbladder > Miscellaneous non-tumor > Papillary hyperplasia
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