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Miscellaneous non-tumor

Hydrops / mucocele

Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 13 February 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.


● Distended gallbladder containing clear and watery (hydrops) or mucoid secretions (mucocele), instead of bile
● Adult cases almost always due to impacted stones in ampulla or cystic duct
● Rarely due to regional tumors causing compression
● Pediatric cases associated with Kawasaki syndrome or other inflammatory narrowing of cystic duct
● Mucoceles that perforate may cause pseudomyxoma peritonei

Case reports

● 24 year old man with right upper quadrant pain with a palpable mass (Prilozi 2011;32:207)
● 31 year old woman with 10 year history of mild, episodic abdominal pain (N Engl J Med 2011;364:e43)
● Massive hydrops mimicking a choledochal cyst (J Pediatr Surg 2011;46:1015)

Gross description

● Thickened gallbladder wall

Micro description

● Fibrous replacement of muscular wall
● Rarely muciphages simulating signet ring adenocarcinoma

● Thin wall with flattened epithelium and sparse inflammation

End of Gallbladder > Miscellaneous non-tumor > Hydrops / mucocele

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