Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 10 February 2013, last major update September 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
● Suggested route for development of invasive carcinoma of gallbladder (Arch Pathol Lab Med 2005;129:386)
Gallstones → chronic inflammation → antral-type metaplasia → intestinal metaplasia → dysplasia → carcinoma
● Major pathway to invasive gallbladder carcinoma is via dysplasia; adenomas do not appear to be important precursors
● Hyperplasia may not be part of this sequence
End of Gallbladder > Dysplasia > Dysplasia-carcinoma sequence
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.
All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at [email protected] with any questions (click here for other contact information).