Benign or non-neoplastic conditions
Reviewer: Nicole Riddle, M.D. (see Reviewers page)
Editor: Jamie Shutter, M.D.
Revised: 10 April 2014, last major update March 2013
Copyright: (c) 2003-2014, PathologyOutlines.com, Inc.
- Benign change of epithelium typically seen during pregnancy or during hormone therapy
- First described in 1954 by Javier Arias Stella, a Peruvian pathologist
- Present in fallopian tube in ~16% of ectopic tubal pregnancies
- Rarely associated with intrauterine pregnancy
- Large epithelioid cells with atypical nuclei; rarely clear cytoplasm
- May also have irregular nuclear membrane, granular chromatin, centronuclear vacuolization, pseudonuclear inclusions
- Early secretory pattern
- Secretory or hypersecretory pattern
- Proliferative or nonsecretory pattern
- Monstrous cell pattern
End of Fallopian tubes > Benign or non-neoplastic conditions > Arias-Stella reaction
Epithelial-cell nuclei enlarged and smudgy
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