Eye
Lacrimal duct / gland
Pleomorphic adenoma-lacrimal duct
Author: Nat Pernick, M.D.
Last author update: 1 February 2014
Last staff update: 27 May 2022
Copyright: 2004-2024, PathologyOutlines.com, Inc.
PubMed Search: Pleomorphic adenoma lacrimal gland
Table of Contents
Definition / general | Treatment | Microscopic (histologic) description | Microscopic (histologic) imagesCite this page: Pernick N. Pleomorphic adenoma-lacrimal duct. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/eyelacrimalpleomorphicadenoma.html. Accessed April 19th, 2024.
Definition / general
- 50 - 60% of lacrimal gland tumors
- Resemble salivary gland tumors of same type
Treatment
- Excisional biopsy with negative margins to prevent recurrence and implantation within the orbit
Microscopic (histologic) description
- Usually encapsulated, composed of benign epithelial and myxoid mesenchymal elements
- Often prominent component of S100+ hyaline cells (presumed myoepithelial origin) with diffuse eosinophilic staining
- May have squamous metaplasia, bone, cartilage or fat
Microscopic (histologic) images
AFIP images
Well circumscribed
pseudoencapsulated
lacrimal gland
tumor
Islands of epithelial cells, myxoid stroma and cysts
Double layer of epithelial cells within a myxoid stroma
Chondroid differentiation
With carcinoma
Large round nodule of pleomorphic adenoma
Benign ducts within
myxoid stroma;
adenocarcinoma
With adenoid cystic carcinoma
