Eye
Eyelid
Other tumors
Actinic keratosis
Author: Deepali Jain, M.D.
Last author update: 1 September 2014
Last staff update: 4 April 2024
Copyright: 2004-2024, PathologyOutlines.com, Inc.
PubMed Search: Actinic keratosis [title] eye
Table of Contents
Definition / general | Case reports | Drawings | Clinical images | Gross description | Microscopic (histologic) description | Microscopic (histologic) images | Differential diagnosisCite this page: Jain D. Actinic keratosis. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/eyeactinickeratosis.html. Accessed April 24th, 2024.
Definition / general
- Also called leukoplakic lesions, ultraviolet light related lesions
- Usually limbal conjunctiva at advancing head of pterygium
Case reports
- 42 year old man with conjunctival mass (Indian J Ophthalmol 2004;52:154)
- 61 year old man with bilateral limbus lesions (J Fr Ophtalmol 1992;15:65)
- 73 year old man with slowly progressive and whitish limbal conjunctival tumor (J Fr Ophtalmol 1998;21:458)
Drawings
Images hosted on other servers:
Darkly pigmented mass,
measuring 4x4 mm on
juxtalimbal conjunctiva
Clinical images
AFIP images
Elevated white limbal tumor
Gross description
- Thickened conjunctiva with leukoplakia
Microscopic (histologic) description
- Sharply demarcated
- Mild atypia of epithelium, acanthosis, parakeratosis, hyperkeratosis but normal polarity, normal maturation
- Elastotic degeneration and lymphocytes in substantia propria
Microscopic (histologic) images
AFIP images
Sharply
demarcated
intraepithelial
lesion
Intraepithelial corneal lesion with severe atypia and parakeratosis
Acantholytic lesion with subepithelial lymphocytes
Atrophic lesion with atypia
Images hosted on other servers:
Mild keratinization with scattered melanophages
Several horn cysts in epithelium
Differential diagnosis
- Carcinoma in situ
- Dysplasia: more diffuse and gelatinous (Can J Ophthalmol 1995;30:312)
