Idiopathic muscular hypertrophy
Reviewer: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 14 June 2013, last major update December 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
- Diffuse thickening of lower esophageal and upper gastric musculature, luminal diameter usually preserved
- Believed to be due to spasm, increased intraluminal pressure
- Adults, no gender preference, rarely familial (autosomal dominant)
- Often asymptomatic; incidental finding at autopsy, sometimes detected during imaging or esophageal motility studies (Chest 1978;73:28)
- May present with dysphagia, chest pain, vomiting, weight loss; patients often diabetic
- Wall is 0.6 to 0.9 cm thick (normal is 0.25 cm)
- Marked uniform thickening of muscularis propria, usually inner circular layer, with variable lymphocytes; no nodules
End of Esophagus > Non-neoplastic disorders > Idiopathic muscular hypertrophy
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