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Esophagus
Premalignant lesions
Barrett's related dysplasia

Reviewer: Elliot Weisenberg, M.D. (see Reviewers page)
Revised: 2 July 2013, last major update April 2013
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

Definition
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Terminology
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Clinical features
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Prognostic factors
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Treatment
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Gross description
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Gross images
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High grade dysplasia

Dysplasia (grade unspecified)

Micro description
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Micro images
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Low grade dysplasia:

Lower half of gland

Upper half of mucosa

Dysplasia in lower half of glands

Pronounced nuclear hyperchromasia

Variable nuclear hyperchromasia


Dysplasia of surface foveolar epithelium

Various images



High grade dysplasia:

Marked distortion of glandular architecture

Various images

Dysplastic epithelium replaces Barrett's mucosa

Cytologic atypia

Various images



Other:

Tubular adenoma

Various images

H&E and CDX2+

Reactive changes

Reactive images (click on links)



Contributed by Dr. Mark R. Wick:

Low grade dysplasia

Metaplasia, high grade dysplasia

Metaplastic

Metaplasia with dysplasia




Positive stains
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Differential diagnosis
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Additional references
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End of Esophagus > Premalignant lesions > Barrett's related dysplasia


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