Colon tumor
Lymphoma and hematopoietic lesions
Mantle cell lymphoma

Author: Charanjeet Singh, M.D. (see Authors page)

Revised: 3 January 2017, last major update February 2012

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PubMed Search: Mantle cell lymphoma colon

Cite this page: Mantle cell lymphoma. PathologyOutlines.com website. http://pathologyoutlines.com/topic/colontumormcl.html. Accessed November 24th, 2017.
Definition / general
Case reports
Gross description
  • Nodular, sessile or polypoid lesions, widely spaced and confluent studded or cobblestone appearance
  • Each polyp 2 mm to 2 cm
  • May be dominant tumor mass in ileocecum
  • Endoscopically normal mucosa may have small tumor infiltrates also
Gross images

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Lymphomatoid polyposis

Microscopic (histologic) description
  • Mantle cells (small lymphocytes with pale cytoplasm and cleaved nuclei), often invasion of submucosa, proliferation around germinal centers and sparing of mucosa
  • Late epithelial invasion and ulceration
  • Note: may also be minute lymphoid infiltrates in known mantle cell patients
Microscopic (histologic) images

Images hosted on other servers:

Figures 2, 3A - 3D

Various images



Nature.com images:

Incidental tumor

Positive stains
Negative stains
Differential diagnosis