Colon tumor
Glassy cell carcinoma

Author: Raul Gonzalez M.D. (see Authors page)

Revised: 28 December 2016, last major update March 2015

Copyright: (c) 2002-2016,, Inc.

PubMed Search: Glassy cell carcinoma [title]

Cite this page: Glassy cell carcinoma of colon. website. Accessed April 25th, 2017.
Definition / General
Micro Description
  • Sheets of malignant cells with ground glass, finely granular cytoplasm
  • Enlarged nuclei with prominent nucleoli
  • Multinucleated cells common
  • Abundant mitotic figures
Micro Images

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From cervix

Positive Stains
Electron Microscopy Description
  • Prominent rough endoplasmic reticulum
Differential Diagnosis
  • Poorly differentiated colorectal carcinoma: glassy cytoplasm absent
  • Focal hCG positivity / production by other carcinomas: more common; other morphologic features absent