Colon tumor
Clear cell carcinoma

Author: Raul Gonzalez M.D. (see Authors page)

Revised: 28 December 2016, last major update March 2015

Copyright: (c) 2002-2016,, Inc.

PubMed Search: "Clear cell carcinoma" colon

Cite this page: Clear cell carcinoma of colon. website. Accessed April 25th, 2017.
Definition / General
  • Rare variant of adenocarcinoma, with fewer than 20 cases reported (Oncol Lett 2014;8:1873)
  • Demonstrates clear cell features due to intracytoplasmic glycogen
Case Reports
Clinical Images

Images hosted on other servers:

Stenotic tumor on colonoscopy

Micro Description
  • Resembles normal colorectal adenocarcinoma, except cells show prominent cytoplasmic clearing
Micro Images

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Glandular arrangement of clear cells

Vesicular nuclei and prominent nucleoli

H&E, CDX2+

Images courtesy of Dr. Raul Gonzalez::

Various images

Various images

Positive Stains