Colon non tumor
Non-neoplastic, non-congenital lesions
Gout

Author: Raul S. Gonzalez, M.D. (see Authors page)

Revised: 9 January 2017, last major update September 2013

Copyright: (c) 2003-2017, PathologyOutlines.com, Inc.

PubMed Search: gout colon
Cite this page: Gout. PathologyOutlines.com website. http://pathologyoutlines.com/topic/colongout.html. Accessed July 21st, 2017.
Definition / general
  • Clinical syndrome due to deposition of urate crystals
  • See topic in joints chapter
Terminology
  • Tophus: deposit of urate crystals, typically in joints or soft tissue
Epidemiology
  • Extremely rare in colon - only one reported case
Pathophysiology
  • Disturbance in purine metabolism leads to increased levels of urate, causing deposits that incite an inflammatory reaction
Clinical features
  • Abdominal pain in colonic gout
Case reports
Treatment
  • Pharmacologic
  • Resection of mass lesions if symptomatic
Gross description
  • Subserosal colonic cyst filled with white-yellow chalky material
Microscopic (histologic) description
  • Subserosal colonic cyst containing needle-shaped polarizable urate crystals (identified with alcohol, not formalin fixation) with surrounding reactive changes