Cite this page: Thrombomodulin. PathologyOutlines.com website. http://pathologyoutlines.com/topic/coagulationthrombomodulin.html. Accessed September 21st, 2017.
Definition / general
- Intrinsic membrane glycoprotein on luminal surface of endothelial cells that binds thrombin and facilitates the activation of protein C
- C/T dimorphism at nucleotide 1418 is associated with premature myocardial infarction, but no definite association with venous thromboembolism
- See also discussion in Stains chapter