CNS tumor
CNS cysts
Rathke cleft cyst

Author: Eman Abdelzaher, M.D., Ph.D. (see Authors page)

Revised: 23 August 2017, last major update February 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: "Rathke cleft cyst"

Cite this page: Abdelzaher, E. Rathke cleft cyst. PathologyOutlines.com website. http://pathologyoutlines.com/topic/cnstumorrathkecyst.html. Accessed September 19th, 2017.
Definition / general
  • Mucus containing cyst arising from Rathke cleft remnants
  • Intrasellar or suprasellar
  • Incidental postmortem finding
  • Larger cysts, usually in adults, may be symptomatic
Radiology images

Images hosted on other servers:

Various images

Gross description
  • Thin walled, mucinous contents
Microscopic (histologic) description
  • Lined by columnar ciliated epithelium with goblet cells
  • Variable fragments of pituitary tissue, squamous metaplasia, xanthogranulomatous reaction
Microscopic (histologic) images

Images hosted on other servers:

Various images

Positive stains
Differential diagnosis