Reviewer: Eman Abdelzaher, M.D., Ph.D. (see Reviewers page)
Revised: 27 April 2013, last major update March 2012
Copyright: (c) 2005-2013, PathologyOutlines.com, Inc.
- Often 5-25 years after treatment of pituitary adenoma or craniopharyngioma
- In children, often follows treatment for acute lymphoblastic leukemia
- Usually anaplastic astrocytoma or glioblastoma
- Similar behavior as non radiation associated gliomas (Tumori 1994;80:220)
- 14 year old with glioma arising 11 years after prophylactic brain radiation and intrathecal methotrexate for ALL (Childs Nerv Syst 1988;4:296)
- 48 year old woman with gliosarcoma arising from irradiated anaplastic ependymoma (Hum Pathol 2004;35:512)
End of CNS tumor > Glial tumors > Post-radiation glioma
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