CNS tumor
Glial tumors
Postradiation glioma

Author: Eman Abdelzaher, M.D., Ph.D. (see Authors page)

Revised: 24 August 2017, last major update March 2012

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Postradiation glioma

Cite this page: Abdelzaher, E. Postradiation glioma. PathologyOutlines.com website. http://pathologyoutlines.com/topic/cnstumorpostradiation.html. Accessed November 19th, 2017.
Definition / general
  • Often 5 - 25 years after treatment of pituitary adenoma or craniopharyngioma
  • In children, often follows treatment for acute lymphoblastic leukemia
  • Usually anaplastic astrocytoma or glioblastoma
  • Similar behavior as nonradiation associated gliomas (Tumori 1994;80:220)
Case reports
  • 14 year old with glioma arising 11 years after prophylactic brain radiation and intrathecal methotrexate for ALL (Childs Nerv Syst 1988;4:296)
  • 48 year old woman with gliosarcoma arising from irradiated anaplastic ependymoma (Hum Pathol 2004;35:512)