CNS tumor
CNS cysts
Endodermal (enterogenous) cyst

Author: Eman Abdelzaher, M.D., Ph.D. (see Authors page)

Revised: 22 August 2017, last major update February 2012

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PubMed Search: Endodermal (enterogenous) cyst

Cite this page: Abdelzaher, E. Endodermal (enterogenous) cyst. PathologyOutlines.com website. http://pathologyoutlines.com/topic/cnstumorenterogenouscyst.html. Accessed November 19th, 2017.
Definition / general
  • Cyst lined by simple columnar epithelium (with or without cilia or mucus globules)
  • Rare, benign; probably of malformative nature
Terminology
  • Also called neurenteric, enteric, enterogenic, bronchogenic, respiratory cyst
Sites
  • Usually intraspinal, rarely intracranial
  • Favored sites: posterior fossa and spinal cord (usually anterior to cord, intradural, extramedullary)
  • All ages are affected: infants, children and adults
Radiology description
  • Like the closely related Rathke cleft cyst and colloid cyst, cyst is often bright on precontrast images
Radiology images

Images hosted on other servers:

MR: cervical neuroenteric cyst

Case reports
Treatment
  • Complete excision; occasionally is adherent to adjacent structures
  • Recurrence may occur
Gross description
  • Usually 1 cm or less, simple, thin walled, filled with opalescent mucinous material
Microscopic (histologic) description
  • Columnar epithelium resting on collagen layer
  • Goblet cells often present
  • Variable cilia, may have squamous metaplasia
  • More complex lesions replicate gastrointestinal or respiratory epithelium (Appl Immunohistochem Mol Morphol 2004;12:230)
Microscopic (histologic) images

Images hosted on other servers:

Ciliated columnar epithelium

Subdural intraspinal cyst

Enteric cyst (H&E)


          

1: MR shows mass at cerebellopontine angle
2: Cyst lining has single or pseudostratified columnal
epithelium with focal squamous metaplasia
3: Cells have prominent apical cilia with basal nuclei but no atypia

Positive stains
Negative stains
Electron microscopy description
  • Well developed stereocilia, distinct basal cells, thin basement membrane
Differential diagnosis