Home   Chapter Home   Jobs   Conferences   Fellowships   Books


CNS tumor

Diffuse astrocytoma - protoplasmic

Reviewers: Eman Abdelzaher, M.D., Ph.D. (see Reviewers page)
Revised: 29 February 2012, last major update February 2012
Copyright: (c) 2005-2012, PathologyOutlines.com, Inc.


● Rare variant; often in temporal and frontal lobes (Am J Clin Pathol 1995;103:705)

Micro description (Histopathology)

● Composed predominantly of uniform cells with small cell bodies and flaccid processes
● Mucoid degeneration and microcysts are common

Micro images

Scant or vacuolated cytoplasm with short processes, vesicular nuclei and prominent nucleoli


Positive stains


Differential diagnosis

● In children, includes pilocytic astrocytoma and pilomyxoid astrocytoma (both are contrast enhancing), oligodendroglioma (1p deletion, Hum Pathol 2004;35:317)

End of CNS tumor > Diffuse astrocytoma - protoplasmic

This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at [email protected] with any questions (click here for other contact information).