CNS tumor
Lymphoma and other hematopoietic lesions
Posttransplantation lymphoproliferative disease (PTLD)

Author: Nat Pernick, M.D. (see Authors page)

Revised: 7 September 2017, last major update January 2006

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: "Posttransplantation lymphoproliferative disease"

Cite this page: Pernick, N. Posttransplantation lymphoproliferative disease (PTLD). PathologyOutlines.com website. http://pathologyoutlines.com/topic/cnstumorPTLD.html. Accessed December 12th, 2017.
Definition / general
  • Associated with organ transplantation or immunosuppression
  • CNS involvement in 19% of cases of PTLD, associated with high mortality (88% at 6 months in one study)
  • Almost all are high grade lymphomas (Am J Clin Pathol 2004;121:246)
  • Lymphoma cases are usually EBV+
Case reports