CNS tumor
Cytopathology Competency Assessment
Reactive and Inflamatory Conditions

Author: Gordon H. Yu, M.D. (see Authors page)

Revised: 27 April 2016, last major update September 2012

Copyright: (c) 2003-2016,, Inc.

PubMed Search: CNS tumor cytopathology

Table of Contents
Medical Knowledge
Cite this page: Cytology/Competency Assessment - Reactive and Inflamatory Conditions. website. Accessed July 26th, 2017.
Medical Knowledge
  1. Infections – Recognize typical cytomorphologic features seen in infections caused by fungal, parasitic, viral and bacterial infections, including:
    1. Morphologic features of organisms themselves (including cytopathic effects)
    2. Background morphologic features (i.e. inflammatory cell components, presence/absence of necrosis)
    3. Typical clinical scenarios and radiologic findings (Systems Based Practice)
      1. Bacterial infections
        • Nocardia
        • Tuberculosis
      2. Viral infections
        • Progressive multifocal leukoencephalopathy (PML) – JC virus
      3. Parasitic infections
        • Toxoplasmosis
        • Neurocysticercosis
  2. Pseudotumoral macrophage-rich lesions
    1. Recognize potential for reactive/inflammatory conditions to demonstrate cytologic findings which may mimic neoplastic lesions (Practice Based Learning)
    2. Recognize typical morphologic findings in:
      1. Infarct
      2. Demyelinating disease