Cervix
Sarcoma / lymphoma / other
Yolk sac tumor

Author: Branko Perunovic, M.D. (see Authors page)

Revised: 2 May 2017, last major update May 2007

Copyright: (c) 2007-2017, PathologyOutlines.com, Inc.

PubMed Search: Yolk sac tumor cervix

Cite this page: Yolk sac tumor. PathologyOutlines.com website. http://pathologyoutlines.com/topic/cervixyst.html. Accessed September 25th, 2017.
Definition / general
  • Also called endodermal sinus tumor
  • More common in vagina; some arise in both areas
  • Usually girls 1 - 2 years old with blood-tinged vaginal discharge and variably elevated serum alpha - fetoprotei
Case reports
Treatment
  • Surgery and chemotherapy
Gross description
  • Partially eroded, pedunculated, soft and friable
Microscopic (histologic) description
  • Reticular (net - like), solid and festoon (string or garland) patterns are most common
  • Usually Schiller - Duval bodies (central blood vessel surrounded by primitive cells)
Microscopic (histologic) images

Images hosted on PathOut server:

Microcystic pattern

Festoon pattern with Schiller - Duval bodies