Urothelial carcinoma

Author: Ashwyna Sunassee, M.D. (see Authors page)

Revised: 26 May 2016, last major update May 2016

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Urothelial carcinoma [title]

Cite this page: Urothelial carcinoma. PathologyOutlines.com website. http://pathologyoutlines.com/topic/cervixurothelialca.html. Accessed April 24th, 2017.
Definition / General
  • Also known as transitional cell carcinoma
Essential Features
  • Has a propensity for late metastasis and local recurrence
  • Potentially aggressive and presents at a more advanced stage
  • Post-menopausal women
  • Cervical epithelium, which is known to undergo benign transitional cell metaplasia, may give rise to benign and malignant transitional cell neoplasms (Am J Surg Pathol 1995;19:1138)
Clinical Features
  • Post-menopausal bleeding or pelvic pain
Case Reports
Micro Description
  • Can be papillary exophytic (most frequent) or inverted-endophytic
  • Papillary structures with thin fibrovascular cores
  • Ovoid cells with abundant eosinophilic cytoplasm (resembles urothelial epithelium)
  • Stromal invasion
Micro Images

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Low and high power views

Cytology Description
Cytology Images

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Metastases to cervix

Positive Stains
Negative Stains
Differential Diagnosis