Benign / non-neoplastic lesions
Pseudosarcomatous fibroepithelial stromal polyps

Author: Dr. Branko Perunovic (see Author page)

Revised: 3 November 2015, last major update May 2007

Copyright: (c) 2007-2015, PathologyOutlines.com, Inc.

PubMed Search: Pseudosarcomatous fibroepithelial stromal polyp

Definition / General
  • Median age 32 years, range 16 to 75 years
  • Often in pregnant patients or post-operative
  • May recur locally; no metastases
  • Positive margin status, which is common, apparently is not associated with recurrence
Gross Description
  • Often multiple lesions, particularly in pregnant women
  • Tender, skin-colored, sac-like
Micro Description
  • Resemble fibroepithelial stromal polyps of vagina and vulva, but with bizarre morphology, frequent mitoses (>10/10 HPF), atypical mitotic figures or hypercellularity
  • Clues to diagnosis are characteristic stellate cells and multinucleate stromal cells, and extension of lesions up to mucosal-submucosal interface
Positive Stains
Differential Diagnosis
Additional References