Cervix
Mesenchymal / mixed epithelial & mesenchymal tumors
Postoperative spindle cell nodule
Author: Branko Perunovic, D.M.
Last author update: 1 May 2007
Last staff update: 5 February 2024 (update in progress)
Copyright: 2007-2024, PathologyOutlines.com, Inc.
PubMed Search: Postoperative spindle cell nodule
Cite this page: Perunovic B. Postoperative spindle cell nodule. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/cervixpostoperativespindlecell.html. Accessed April 19th, 2024.
Definition / general
- Associated with prior biopsy or curettage
- More common in vulva / vagina (Histopathology 1995;26:571) or bladder (J Urol 1990;143:824)
- May recur after excision
Microscopic (histologic) description
- Resembles nodular fasciitis and granulation tissue
- Bundles or fascicles of proliferative spindle cells with infiltrative margins
- Nuclei are oval to spindled with mild hyperchromasia and pleomorphism
- Frequent mitotic figures
- Often edematous stroma, delicate capillary network, neutrophils and red blood cells
