Author: Branko Perunovic, M.D. (see Authors page)

Revised: 3 May 2017, last major update May 2007

Copyright: (c) 2007-2017, PathologyOutlines.com, Inc.

PubMed Search: "metastatic to" cervix

Cite this page: Metastases. PathologyOutlines.com website. http://pathologyoutlines.com/topic/cervixmets.html. Accessed October 22nd, 2017.
Definition / general
  • Extragenital tumors more commonly metastasize to ovary and vagina than cervix
  • Usually from ovary, breast, colon (Arch Pathol Lab Med 2003;127:1586), stomach, kidney; evidence of widespread disease is usually present
  • Direct extension from endometrial primary tumor is also common (particularly poorly differentiated adenocarcinoma)
  • Often involves cervical stroma and NOT surface epithelium or endocervical glands
  • Rarely due to metastatic mucinous carcinoma of appendix
Case reports
Microscopic (histologic) description
  • Usually no in situ component
  • Extensive angiolymphatic invasion is present, even in small and superficial lesions
Microscopic (histologic) images

Images hosted on PathOut server:

Breast carcinoma metastatic to cervix (AFIP)

Case of week #125 (metastatic lobular carcinoma to endometrial polyp):

Various images




Cytology description