Table of ContentsDefinition / general | Etiology | Clinical features | Cytology description | Cytology images
Cite this page: Parakeratosis. PathologyOutlines.com website. http://pathologyoutlines.com/topic/cervixcytologyparakeratosis.html. Accessed May 23rd, 2017.
Definition / general
- Defined histologically as abnormal keratinization of the squamous epithelium with persistence of the cell nuclei in the superficial cells
- Due to SIL or infection
- Associated with dysplasia more commonly than hyperkeratosis
- Usually small, round or polygonal squamous cells with dense orangophilic to eosinophilic cytoplasm and pyknotic nuclei
- Single flat cells, layered strips or "pearls"
- Can be associated with inflammation (like fungus)
- May be associated with SIL (Am J Obstet Gynecol 2002;187:997)
- SIL cases tend to have irregular chromatin clumping, irregular nuclear membranes, disorganized growth pattern, less hyperkeratosis (Diagn Cytopathol 1997;17:447)