Cervix - Cytology
Benign cells / nonneoplastic lesions
Maturation index

Author: Nat Pernick, M.D. (see Authors page)

Revised: 18 May 2017, last major update June 2011

Copyright: (c) 2011-2017, PathologyOutlines.com, Inc.

PubMed search: Maturation index [title]

Table of Contents
Definition / general
Cite this page: Maturation index. PathologyOutlines.com website. http://pathologyoutlines.com/topic/cervixcytologymaturationindex.html. Accessed December 15th, 2017.
Definition / general
  • Defined as ratio of parabasal to intermediate to superficial cells of vaginal epithelium (sampled at middle third of lateral vaginal wall)
  • Sample often obtained simultaneous with Pap smear
  • For detecting hormonal effects in menopausal and postmenopausal women
  • Increased maturation in vaginal epithelium may be due to estrogenic effect of tamoxifen (Clin Exp Obstet Gynecol 1998;25:121)